Connectivity Map Analysis of a Single-Cell RNA-Sequencing -Derived Transcriptional Signature of mTOR Signaling

In the connectivity map (CMap) approach to drug repositioning and development, transcriptional signature of disease is constructed by differential gene expression analysis between the diseased tissue or cells and the control. The negative correlation between the transcriptional disease signature and...

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Detalles Bibliográficos
Autores principales: Al Mahi, Naim, Zhang, Erik Y., Sherman, Susan, Yu, Jane J., Medvedovic, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122562/
https://www.ncbi.nlm.nih.gov/pubmed/33922083
http://dx.doi.org/10.3390/ijms22094371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122562/
https://www.ncbi.nlm.nih.gov/pubmed/33922083
http://dx.doi.org/10.3390/ijms22094371

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