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Three-Component Reactions of 3-Arylidene-3H-Indolium Salts, Isocyanides and Amines

A multicomponent reaction of isocyanides with aryl(indol-3-yl)methylium salts and amines has been found. A series of aryl(indol-3-yl)acetimidamides was obtained in up to 96% yields. In the case of ethyl isocyanoacetate, the reaction is followed by cyclization to form 3,5-dihydro-4H-imidazol-4-one de...

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Detalles Bibliográficos
Autores principales: Nguyen, Hung M., Golantsov, Nikita E., Golubenkova, Alexandra S., Rybakov, Victor B., Voskressensky, Leonid G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122609/
https://www.ncbi.nlm.nih.gov/pubmed/33919009
http://dx.doi.org/10.3390/molecules26092402