Three-Component Reactions of 3-Arylidene-3H-Indolium Salts, Isocyanides and Amines

A multicomponent reaction of isocyanides with aryl(indol-3-yl)methylium salts and amines has been found. A series of aryl(indol-3-yl)acetimidamides was obtained in up to 96% yields. In the case of ethyl isocyanoacetate, the reaction is followed by cyclization to form 3,5-dihydro-4H-imidazol-4-one de...

Descripción completa

Detalles Bibliográficos
Autores principales: Nguyen, Hung M., Golantsov, Nikita E., Golubenkova, Alexandra S., Rybakov, Victor B., Voskressensky, Leonid G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122609/
https://www.ncbi.nlm.nih.gov/pubmed/33919009
http://dx.doi.org/10.3390/molecules26092402
_version_ 1783692663942283264
author Nguyen, Hung M.
Golantsov, Nikita E.
Golubenkova, Alexandra S.
Rybakov, Victor B.
Voskressensky, Leonid G.
author_facet Nguyen, Hung M.
Golantsov, Nikita E.
Golubenkova, Alexandra S.
Rybakov, Victor B.
Voskressensky, Leonid G.
author_sort Nguyen, Hung M.
collection PubMed
description A multicomponent reaction of isocyanides with aryl(indol-3-yl)methylium salts and amines has been found. A series of aryl(indol-3-yl)acetimidamides was obtained in up to 96% yields. In the case of ethyl isocyanoacetate, the reaction is followed by cyclization to form 3,5-dihydro-4H-imidazol-4-one derivatives.
format Online
Article
Text
id pubmed-8122609
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-81226092021-05-16 Three-Component Reactions of 3-Arylidene-3H-Indolium Salts, Isocyanides and Amines Nguyen, Hung M. Golantsov, Nikita E. Golubenkova, Alexandra S. Rybakov, Victor B. Voskressensky, Leonid G. Molecules Article A multicomponent reaction of isocyanides with aryl(indol-3-yl)methylium salts and amines has been found. A series of aryl(indol-3-yl)acetimidamides was obtained in up to 96% yields. In the case of ethyl isocyanoacetate, the reaction is followed by cyclization to form 3,5-dihydro-4H-imidazol-4-one derivatives. MDPI 2021-04-21 /pmc/articles/PMC8122609/ /pubmed/33919009 http://dx.doi.org/10.3390/molecules26092402 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nguyen, Hung M.
Golantsov, Nikita E.
Golubenkova, Alexandra S.
Rybakov, Victor B.
Voskressensky, Leonid G.
Three-Component Reactions of 3-Arylidene-3H-Indolium Salts, Isocyanides and Amines
title Three-Component Reactions of 3-Arylidene-3H-Indolium Salts, Isocyanides and Amines
title_full Three-Component Reactions of 3-Arylidene-3H-Indolium Salts, Isocyanides and Amines
title_fullStr Three-Component Reactions of 3-Arylidene-3H-Indolium Salts, Isocyanides and Amines
title_full_unstemmed Three-Component Reactions of 3-Arylidene-3H-Indolium Salts, Isocyanides and Amines
title_short Three-Component Reactions of 3-Arylidene-3H-Indolium Salts, Isocyanides and Amines
title_sort three-component reactions of 3-arylidene-3h-indolium salts, isocyanides and amines
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122609/
https://www.ncbi.nlm.nih.gov/pubmed/33919009
http://dx.doi.org/10.3390/molecules26092402
work_keys_str_mv AT nguyenhungm threecomponentreactionsof3arylidene3hindoliumsaltsisocyanidesandamines
AT golantsovnikitae threecomponentreactionsof3arylidene3hindoliumsaltsisocyanidesandamines
AT golubenkovaalexandras threecomponentreactionsof3arylidene3hindoliumsaltsisocyanidesandamines
AT rybakovvictorb threecomponentreactionsof3arylidene3hindoliumsaltsisocyanidesandamines
AT voskressenskyleonidg threecomponentreactionsof3arylidene3hindoliumsaltsisocyanidesandamines

Ejemplares similares