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Effects of Whole-Body Adenylyl Cyclase 5 (Adcy5) Deficiency on Systemic Insulin Sensitivity and Adipose Tissue

Genome-wide association studies have identified adenylyl cyclase type 5 (ADCY5) as candidate gene for diabetes-related quantitative traits and an increased risk of type 2 diabetes. Mice with a whole-body deletion of Adcy5 (Adcy5(–/–)) do not develop obesity, glucose intolerance and insulin resistanc...

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Detalles Bibliográficos
Autores principales: Dommel, Sebastian, Hoffmann, Anne, Berger, Claudia, Kern, Matthias, Klöting, Nora, Kannt, Aimo, Blüher, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122634/
https://www.ncbi.nlm.nih.gov/pubmed/33919448
http://dx.doi.org/10.3390/ijms22094353