Hypophosphatasia: A Unique Disorder of Bone Mineralization

Hypophosphatasia (HPP) is a rare genetic disease characterized by a decrease in the activity of tissue non-specific alkaline phosphatase (TNSALP). TNSALP is encoded by the ALPL gene, which is abundantly expressed in the skeleton, liver, kidney, and developing teeth. HPP exhibits high clinical variab...

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Detalles Bibliográficos
Autores principales: Villa-Suárez, Juan Miguel, García-Fontana, Cristina, Andújar-Vera, Francisco, González-Salvatierra, Sheila, de Haro-Muñoz, Tomás, Contreras-Bolívar, Victoria, García-Fontana, Beatriz, Muñoz-Torres, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122659/
https://www.ncbi.nlm.nih.gov/pubmed/33919113
http://dx.doi.org/10.3390/ijms22094303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122659/
https://www.ncbi.nlm.nih.gov/pubmed/33919113
http://dx.doi.org/10.3390/ijms22094303

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