Single Cell Gene Expression Analysis in a 3D Microtissue Liver Model Reveals Cell Type-Specific Responses to Pro-Fibrotic TGF-β1 Stimulation

3D cell culture systems are widely used to study disease mechanisms and therapeutic interventions. Multicellular liver microtissues (MTs) comprising HepaRG, hTERT-HSC and THP-1 maintain multicellular interactions and physiological properties required to mimic liver fibrosis. However, the inherent co...

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Detalles Bibliográficos
Autores principales: Messner, Catherine Jane, Babrak, Lmar, Titolo, Gaia, Caj, Michaela, Miho, Enkelejda, Suter-Dick, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122664/
https://www.ncbi.nlm.nih.gov/pubmed/33922101
http://dx.doi.org/10.3390/ijms22094372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122664/
https://www.ncbi.nlm.nih.gov/pubmed/33922101
http://dx.doi.org/10.3390/ijms22094372

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