New Succinimides with Potent Anticancer Activity: Synthesis, Activation of Stress Signaling Pathways and Characterization of Apoptosis in Leukemia and Cervical Cancer Cells

Based on previously identified dicarboximides with significant anticancer and immunomodulatory activities, a series of 26 new derivatives were designed and synthesized by the Diels–Alder reaction between appropriate diene and maleimide or hydroxymaleimide moieties. The resulting imides were function...

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Detalles Bibliográficos
Autores principales: Cieślak, Marcin, Napiórkowska, Mariola, Kaźmierczak-Barańska, Julia, Królewska-Golińska, Karolina, Hawrył, Anna, Wybrańska, Iwona, Nawrot, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122671/
https://www.ncbi.nlm.nih.gov/pubmed/33919224
http://dx.doi.org/10.3390/ijms22094318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122671/
https://www.ncbi.nlm.nih.gov/pubmed/33919224
http://dx.doi.org/10.3390/ijms22094318

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