Inhibition of the Myocardin-Related Transcription Factor Pathway Increases Efficacy of Trametinib in NRAS-Mutant Melanoma Cell Lines

SIMPLE SUMMARY: Malignant melanoma is the most aggressive skin cancer, and treatment is often ineffective due to the development of resistance to targeted therapeutic agents. The most prevalent form of melanoma with a mutated BRAF gene has an effective treatment, but the second most common mutation...

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Detalles Bibliográficos
Autores principales: Appleton, Kathryn M., Palsuledesai, Charuta C., Misek, Sean A., Blake, Maja, Zagorski, Joseph, Gallo, Kathleen A., Dexheimer, Thomas S., Neubig, Richard R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122681/
https://www.ncbi.nlm.nih.gov/pubmed/33921974
http://dx.doi.org/10.3390/cancers13092012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122681/
https://www.ncbi.nlm.nih.gov/pubmed/33921974
http://dx.doi.org/10.3390/cancers13092012

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