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The Role of NRF2/KEAP1 Signaling Pathway in Cancer Metabolism

The nuclear factor-erythroid 2 p45-related factor 2 (NRF2, also called Nfe2l2) and its cytoplasmic repressor, Kelch-like ECH-associated protein 1 (KEAP1), are major regulators of redox homeostasis controlling a multiple of genes for detoxification and cytoprotective enzymes. The NRF2/KEAP1 pathway i...

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Detalles Bibliográficos
Autores principales: Song, Moon-Young, Lee, Da-Young, Chun, Kyung-Soo, Kim, Eun-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122702/
https://www.ncbi.nlm.nih.gov/pubmed/33922165
http://dx.doi.org/10.3390/ijms22094376