Inhibition of the Histone Methyltransferase EZH2 Enhances Protumor Monocyte Recruitment in Human Mesothelioma Spheroids

Malignant pleural mesothelioma (MPM) is a highly aggressive cancer with a long latency period and dismal prognosis. Recently, tazemetostat (EPZ-6438), an inhibitor of the histone methyltransferase EZH2, has entered clinical trials due to the antiproliferative effects reported on MPM cells. However,...

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Detalles Bibliográficos
Autores principales: Mola, Silvia, Pinton, Giulia, Erreni, Marco, Corazzari, Marco, De Andrea, Marco, Grolla, Ambra A., Martini, Veronica, Moro, Laura, Porta, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122808/
https://www.ncbi.nlm.nih.gov/pubmed/33922336
http://dx.doi.org/10.3390/ijms22094391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122808/
https://www.ncbi.nlm.nih.gov/pubmed/33922336
http://dx.doi.org/10.3390/ijms22094391

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