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Inhibition of the Histone Methyltransferase EZH2 Enhances Protumor Monocyte Recruitment in Human Mesothelioma Spheroids
Malignant pleural mesothelioma (MPM) is a highly aggressive cancer with a long latency period and dismal prognosis. Recently, tazemetostat (EPZ-6438), an inhibitor of the histone methyltransferase EZH2, has entered clinical trials due to the antiproliferative effects reported on MPM cells. However,...
Autores principales: | Mola, Silvia, Pinton, Giulia, Erreni, Marco, Corazzari, Marco, De Andrea, Marco, Grolla, Ambra A., Martini, Veronica, Moro, Laura, Porta, Chiara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122808/ https://www.ncbi.nlm.nih.gov/pubmed/33922336 http://dx.doi.org/10.3390/ijms22094391 |
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