Inhibition of Glycolysis Suppresses Cell Proliferation and Tumor Progression In Vivo: Perspectives for Chronotherapy

A high rate of glycolysis is considered a hallmark of tumor progression and is caused by overexpression of the enzyme 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3). Therefore, we analyzed the possibility of inhibiting tumor and endothelial cell metabolism through the inhibition of P...

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Detalles Bibliográficos
Autores principales: Horváthová, Jana, Moravčík, Roman, Matúšková, Miroslava, Šišovský, Vladimír, Boháč, Andrej, Zeman, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122821/
https://www.ncbi.nlm.nih.gov/pubmed/33922320
http://dx.doi.org/10.3390/ijms22094390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122821/
https://www.ncbi.nlm.nih.gov/pubmed/33922320
http://dx.doi.org/10.3390/ijms22094390

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