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Inhibition of Glycolysis Suppresses Cell Proliferation and Tumor Progression In Vivo: Perspectives for Chronotherapy
A high rate of glycolysis is considered a hallmark of tumor progression and is caused by overexpression of the enzyme 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3). Therefore, we analyzed the possibility of inhibiting tumor and endothelial cell metabolism through the inhibition of P...
Autores principales: | Horváthová, Jana, Moravčík, Roman, Matúšková, Miroslava, Šišovský, Vladimír, Boháč, Andrej, Zeman, Michal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122821/ https://www.ncbi.nlm.nih.gov/pubmed/33922320 http://dx.doi.org/10.3390/ijms22094390 |
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