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Modeling Sialidosis with Neural Precursor Cells Derived from Patient-Derived Induced Pluripotent Stem Cells

Sialidosis, caused by a genetic deficiency of the lysosomal sialidase gene (NEU1), is a systemic disease involving various tissues and organs, including the nervous system. Understanding the neurological dysfunction and pathology associated with sialidosis remains a challenge, partially due to the l...

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Detalles Bibliográficos
Autores principales: Seol, Binna, Kim, Young-Dae, Cho, Yee Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122832/
https://www.ncbi.nlm.nih.gov/pubmed/33922276
http://dx.doi.org/10.3390/ijms22094386