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Targeting Cancer Stem Cells with Differentiation Agents as an Alternative to Genotoxic Chemotherapy for the Treatment of Malignant Testicular Germ Cell Tumors

SIMPLE SUMMARY: Testicular germ cell tumors (TGCTs) are the most common solid malignancy in young men. Fortunately, these tumors are highly curable with conventional genotoxic chemotherapy. However, because these chemotherapeutics have significant short- and long-term side effects, less toxic treatm...

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Detalles Bibliográficos
Autores principales: Loehr, Amanda R., Pierpont, Timothy M., Gelsleichter, Eric, Galang, Anabella Maria D., Fernandez, Irma R., Moore, Elizabeth S., Guo, Matthew Z., Miller, Andrew D., Weiss, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122873/
https://www.ncbi.nlm.nih.gov/pubmed/33922599
http://dx.doi.org/10.3390/cancers13092045