Targeting S1PRs as a Therapeutic Strategy for Inflammatory Bone Loss Diseases—Beyond Regulating S1P Signaling

As G protein coupled receptors, sphingosine-1-phosphate receptors (S1PRs) have recently gained attention for their role in modulating inflammatory bone loss diseases. Notably, in murine studies inhibiting S1PR2 by its specific inhibitor, JTE013, alleviated osteoporosis induced by RANKL and attenuate...

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Detalles Bibliográficos
Autor principal: Yu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122917/
https://www.ncbi.nlm.nih.gov/pubmed/33922596
http://dx.doi.org/10.3390/ijms22094411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122917/
https://www.ncbi.nlm.nih.gov/pubmed/33922596
http://dx.doi.org/10.3390/ijms22094411

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