The Bone Marrow Niche in B-Cell Acute Lymphoblastic Leukemia: The Role of Microenvironment from Pre-Leukemia to Overt Leukemia

Genetic lesions predisposing to pediatric B-cell acute lymphoblastic leukemia (B-ALL) arise in utero, generating a clinically silent pre-leukemic phase. We here reviewed the role of the surrounding bone marrow (BM) microenvironment in the persistence and transformation of pre-leukemic clones into fu...

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Detalles Bibliográficos
Autores principales: Dander, Erica, Palmi, Chiara, D’Amico, Giovanna, Cazzaniga, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122951/
https://www.ncbi.nlm.nih.gov/pubmed/33922612
http://dx.doi.org/10.3390/ijms22094426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122951/
https://www.ncbi.nlm.nih.gov/pubmed/33922612
http://dx.doi.org/10.3390/ijms22094426

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