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Transthyretin Misfolding, A Fatal Structural Pathogenesis Mechanism

Transthyretin (TTR) is an essential transporter of a thyroid hormone and a holo-retinol binding protein, found abundantly in human plasma and cerebrospinal fluid. In addition, this protein is infamous for its amyloidogenic propensity, causing various amyloidoses in humans, such as senile systemic am...

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Detalles Bibliográficos
Autores principales: Si, Jin-Beom, Kim, Bokyung, Kim, Jin Hae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122960/
https://www.ncbi.nlm.nih.gov/pubmed/33922648
http://dx.doi.org/10.3390/ijms22094429