The PARP Enzyme Family and the Hallmarks of Cancer Part 1. Cell Intrinsic Hallmarks

SIMPLE SUMMARY: Poly (ADP-ribose) polymerase (PARP) proteins regulate DNA damage correction, replication, and gene transcription. By controlling pivotal aspects of these processes, PARPs are heavily implicated in cancer development. Inhibitors of PARPs, approved for cancer chemotherapy a few years a...

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Detalles Bibliográficos
Autores principales: Demény, Máté A., Virág, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122967/
https://www.ncbi.nlm.nih.gov/pubmed/33922595
http://dx.doi.org/10.3390/cancers13092042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122967/
https://www.ncbi.nlm.nih.gov/pubmed/33922595
http://dx.doi.org/10.3390/cancers13092042

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