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Metformin Protects against NMDA-Induced Retinal Injury through the MEK/ERK Signaling Pathway in Rats

Metformin, an anti-hyperglycemic drug of the biguanide class, exerts positive effects in several non-diabetes-related diseases. In this study, we aimed to examine the protective effects of metformin against N-methyl-D-aspartic acid (NMDA)-induced excitotoxic retinal damage in rats and determine the...

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Detalles Bibliográficos
Autores principales: Watanabe, Koki, Asano, Daiki, Ushikubo, Hiroko, Morita, Akane, Mori, Asami, Sakamoto, Kenji, Ishii, Kunio, Nakahara, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123037/
https://www.ncbi.nlm.nih.gov/pubmed/33922757
http://dx.doi.org/10.3390/ijms22094439