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Discovery–Versus Hypothesis–Driven Detection of Protein–Protein Interactions and Complexes
Protein complexes are the main functional modules in the cell that coordinate and perform the vast majority of molecular functions. The main approaches to identify and quantify the interactome to date are based on mass spectrometry (MS). Here I summarize the benefits and limitations of different MS-...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123138/ https://www.ncbi.nlm.nih.gov/pubmed/33923221 http://dx.doi.org/10.3390/ijms22094450 |