An Update on Glioblastoma Biology, Genetics, and Current Therapies: Novel Inhibitors of the G Protein-Coupled Receptor CCR5

The mechanisms governing therapeutic resistance of the most aggressive and lethal primary brain tumor in adults, glioblastoma, have increasingly focused on tumor stem cells. These cells, protected by the periarteriolar hypoxic GSC niche, contribute to the poor efficacy of standard of care treatment...

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Detalles Bibliográficos
Autores principales: Lah Turnšek, Tamara, Jiao, Xuanmao, Novak, Metka, Jammula, Sriharsha, Cicero, Gina, Ashton, Anthony W., Joyce, David, Pestell, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123168/
https://www.ncbi.nlm.nih.gov/pubmed/33923334
http://dx.doi.org/10.3390/ijms22094464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123168/
https://www.ncbi.nlm.nih.gov/pubmed/33923334
http://dx.doi.org/10.3390/ijms22094464

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