A Yeast-Based Screening Unravels Potential Therapeutic Molecules for Mitochondrial Diseases Associated with Dominant ANT1 Mutations

Mitochondrial diseases result from inherited or spontaneous mutations in mitochondrial or nuclear DNA, leading to an impairment of the oxidative phosphorylation responsible for the synthesis of ATP. To date, there are no effective pharmacological therapies for these pathologies. We performed a yeast...

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Detalles Bibliográficos
Autores principales: di Punzio, Giulia, Di Noia, Maria Antonietta, Delahodde, Agnès, Sellem, Carole, Donnini, Claudia, Palmieri, Luigi, Lodi, Tiziana, Dallabona, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123201/
https://www.ncbi.nlm.nih.gov/pubmed/33923309
http://dx.doi.org/10.3390/ijms22094461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123201/
https://www.ncbi.nlm.nih.gov/pubmed/33923309
http://dx.doi.org/10.3390/ijms22094461

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