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Leptin Receptor Compound Heterozygosity in Humans and Animal Models

Leptin and its receptor are essential for regulating food intake, energy expenditure, glucose homeostasis and fertility. Mutations within leptin or the leptin receptor cause early-onset obesity and hyperphagia, as described in human and animal models. The effect of both heterozygous and homozygous v...

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Detalles Bibliográficos
Autores principales: Berger, Claudia, Klöting, Nora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123313/
https://www.ncbi.nlm.nih.gov/pubmed/33922961
http://dx.doi.org/10.3390/ijms22094475