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Leptin Receptor Compound Heterozygosity in Humans and Animal Models
Leptin and its receptor are essential for regulating food intake, energy expenditure, glucose homeostasis and fertility. Mutations within leptin or the leptin receptor cause early-onset obesity and hyperphagia, as described in human and animal models. The effect of both heterozygous and homozygous v...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123313/ https://www.ncbi.nlm.nih.gov/pubmed/33922961 http://dx.doi.org/10.3390/ijms22094475 |