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TLR4-Mediated Recognition of Mouse Polyomavirus Promotes Cancer-Associated Fibroblast-Like Phenotype and Cell Invasiveness

SIMPLE SUMMARY: Mouse polyomavirus (MPyV) is widely used as a model for cancer development studies. In many preceding studies, its tumorigenic potential was attributed to a virus protein called middle T antigen (MT), which possesses a transforming ability through activation of cell-associated tyrosi...

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Detalles Bibliográficos
Autores principales: Janovec, Vaclav, Ryabchenko, Boris, Škarková, Aneta, Pokorná, Karolína, Rösel, Daniel, Brábek, Jan, Weber, Jan, Forstová, Jitka, Hirsch, Ivan, Huérfano, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123340/
https://www.ncbi.nlm.nih.gov/pubmed/33923020
http://dx.doi.org/10.3390/cancers13092076