Cytoguardin: A Tryptophan Metabolite against Cancer Growth and Metastasis

Cytoguardin was identified in the conditioned medium of fibroblasts as a tryptophan metabolite, 5-methoxytryptophan (5-MTP). It is synthesized via two enzymatic steps: tryptophan hydroxylase (TPH) and hydroxyindole O-methyltransferase (HIOMT). A truncated HIOMT isoform, HIOMT298, catalyzes 5-MTP syn...

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Detalles Bibliográficos
Autor principal: Wu, Kenneth K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123408/
https://www.ncbi.nlm.nih.gov/pubmed/33925793
http://dx.doi.org/10.3390/ijms22094490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123408/
https://www.ncbi.nlm.nih.gov/pubmed/33925793
http://dx.doi.org/10.3390/ijms22094490

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