The Potential Role of Small-Molecule PERK Inhibitor LDN-0060609 in Primary Open-Angle Glaucoma Treatment

Primary open-angle glaucoma (POAG) constitutes the most common type of glaucoma. Emerging evidence suggests that Endoplasmic Reticulum (ER) stress and the protein kinase RNA-like endoplasmic reticulum kinase (PERK)-mediated Unfolded Protein Response (UPR) signaling pathway play a key role in POAG pa...

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Detalles Bibliográficos
Autores principales: Rozpędek-Kamińska, Wioletta, Galita, Grzegorz, Siwecka, Natalia, Carroll, Steven L., Diehl, John Alan, Kucharska, Ewa, Pytel, Dariusz, Majsterek, Ireneusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123501/
https://www.ncbi.nlm.nih.gov/pubmed/33925820
http://dx.doi.org/10.3390/ijms22094494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123501/
https://www.ncbi.nlm.nih.gov/pubmed/33925820
http://dx.doi.org/10.3390/ijms22094494

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