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Antisense oligonucleotide‐mediated knockdown of Mpzl3 attenuates the negative metabolic effects of diet‐induced obesity in mice

Previously, we demonstrated that global knockout (KO) of the gene encoding myelin protein zero‐like 3 (Mpzl3) results in reduced body weight and adiposity, increased energy expenditure, and reduced hepatic lipid synthesis in mice. These mice also exhibit cyclic and progressive alopecia which may con...

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Detalles Bibliográficos
Autores principales: Worley, Beth L., Auen, Thomas, Arnold, Amy C., Monia, Brett P., Hempel, Nadine, Czyzyk, Traci A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123547/
https://www.ncbi.nlm.nih.gov/pubmed/33991450
http://dx.doi.org/10.14814/phy2.14853