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Prevention of non‐alcoholic steatohepatitis by long‐term exercise via the induction of phenotypic changes in Kupffer cells of hyperphagic obese mice

Exercise ameliorates nonalcoholic fatty liver disease (NAFLD) by inducing phenotypic changes in Kupffer cells (KCs). p62/Sqstm1‐knockout (p62‐KO) mice develop NAFLD alongside hyperphagia‐induced obesity. We evaluated (1) the effects of long‐term exercise on the foreign‐body phagocytic capacity of KC...

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Detalles Bibliográficos
Autores principales: Miura, Ikuru, Komine, Shoichi, Okada, Kosuke, Wada, Shota, Warabi, Eiji, Uchida, Fumihiko, Oh, Sechang, Suzuki, Hideo, Mizokami, Yuji, Shoda, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123550/
https://www.ncbi.nlm.nih.gov/pubmed/33991461
http://dx.doi.org/10.14814/phy2.14859