A Germline-Encoded Structural Arginine Trap Underlies the Anti-DNA Reactivity of a Murine V Gene Segment

Autoimmunity may have its origins of early repertoire selection in developmental B cells. Such a primary repertoire is probably shaped by selecting B cells that can efficiently perform productive signaling, stimulated by self-antigens in the bone marrow, such as DNA. In support of that idea, we prev...

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Detalles Bibliográficos
Autores principales: dos Santos Araújo, Ronny Petterson, França, Renato Kaylan Alves, Valadares, Napoleão Fonseca, Maranhão, Andrea Queiroz, Brigido, Marcelo Macedo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123574/
https://www.ncbi.nlm.nih.gov/pubmed/33926148
http://dx.doi.org/10.3390/ijms22094541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123574/
https://www.ncbi.nlm.nih.gov/pubmed/33926148
http://dx.doi.org/10.3390/ijms22094541

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