NEIL1 and NEIL2 Are Recruited as Potential Backup for OGG1 upon OGG1 Depletion or Inhibition by TH5487

DNA damage caused by reactive oxygen species may result in genetic mutations or cell death. Base excision repair (BER) is the major pathway that repairs DNA oxidative damage in order to maintain genomic integrity. In mammals, eleven DNA glycosylases have been reported to initiate BER, where each rec...

Descripción completa

Detalles Bibliográficos
Autores principales: Hanna, Bishoy M. F., Michel, Maurice, Helleday, Thomas, Mortusewicz, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123590/
https://www.ncbi.nlm.nih.gov/pubmed/33925271
http://dx.doi.org/10.3390/ijms22094542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123590/
https://www.ncbi.nlm.nih.gov/pubmed/33925271
http://dx.doi.org/10.3390/ijms22094542

Ejemplares similares