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Efficacy of the Piperidine Nitroxide 4-MethoxyTEMPO in Ameliorating Serum Amyloid A-Mediated Vascular Inflammation

Intracellular redox imbalance in endothelial cells (EC) can lead to endothelial dysfunction, which underpins cardiovascular diseases (CVD). The acute phase serum amyloid A (SAA) elicits inflammation through stimulating production of reactive oxygen species (ROS). The cyclic nitroxide 4-MethoxyTEMPO...

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Detalles Bibliográficos
Autores principales: Martin, Nathan J., Chami, Belal, Vallejo, Abigail, Mojadadi, Albaraa A., Witting, Paul K., Ahmad, Gulfam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123591/
https://www.ncbi.nlm.nih.gov/pubmed/33925294
http://dx.doi.org/10.3390/ijms22094549