Development of Novel Potential Pleiotropic Compounds of Interest in Alzheimer’s Disease Treatment through Rigidification Strategy

The development of Multi-Target Directed Ligand is of clear interest for the treatment of multifactorial pathology such as Alzheimer’s disease (AD). In this context, acetylcholinesterase (AChE) inhibitors have been modulated in order to generate novel pleiotropic compounds targeting a second protein...

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Detalles Bibliográficos
Autores principales: Lecoutey, Cédric, Legay, Rémi, Davis, Audrey, Sopková-de Oliveira Santos, Jana, Dallemagne, Patrick, Rochais, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123621/
https://www.ncbi.nlm.nih.gov/pubmed/33926141
http://dx.doi.org/10.3390/molecules26092536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123621/
https://www.ncbi.nlm.nih.gov/pubmed/33926141
http://dx.doi.org/10.3390/molecules26092536

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