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Development of Novel Potential Pleiotropic Compounds of Interest in Alzheimer’s Disease Treatment through Rigidification Strategy
The development of Multi-Target Directed Ligand is of clear interest for the treatment of multifactorial pathology such as Alzheimer’s disease (AD). In this context, acetylcholinesterase (AChE) inhibitors have been modulated in order to generate novel pleiotropic compounds targeting a second protein...
Autores principales: | Lecoutey, Cédric, Legay, Rémi, Davis, Audrey, Sopková-de Oliveira Santos, Jana, Dallemagne, Patrick, Rochais, Christophe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123621/ https://www.ncbi.nlm.nih.gov/pubmed/33926141 http://dx.doi.org/10.3390/molecules26092536 |
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