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Supramolecular Polymorphism of (G(4)C(2))(n) Repeats Associated with ALS and FTD

Guanine-rich DNA sequences self-assemble into highly stable fourfold structures known as DNA-quadruplexes (or G-quadruplexes). G-quadruplexes have furthermore the tendency to associate into one-dimensional supramolecular aggregates termed G-wires. We studied the formation of G-wires in solutions of...

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Detalles Bibliográficos
Autores principales: Potrč, Melani, Sebastián, Nerea, Škarabot, Miha, Drevenšek-Olenik, Irena, Spindler, Lea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123662/
https://www.ncbi.nlm.nih.gov/pubmed/33926081
http://dx.doi.org/10.3390/ijms22094532