Cargando…

Supramolecular Polymorphism of (G(4)C(2))(n) Repeats Associated with ALS and FTD

Guanine-rich DNA sequences self-assemble into highly stable fourfold structures known as DNA-quadruplexes (or G-quadruplexes). G-quadruplexes have furthermore the tendency to associate into one-dimensional supramolecular aggregates termed G-wires. We studied the formation of G-wires in solutions of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Potrč, Melani, Sebastián, Nerea, Škarabot, Miha, Drevenšek-Olenik, Irena, Spindler, Lea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123662/ https://www.ncbi.nlm.nih.gov/pubmed/33926081 http://dx.doi.org/10.3390/ijms22094532

Ejemplares similares

Understanding self-assembly at molecular level enables controlled design of DNA G-wires of different properties
por: Pavc, Daša, et al.
Publicado: (2022)

GC ends control topology of DNA G-quadruplexes and their cation-dependent assembly
por: Pavc, Daša, et al.
Publicado: (2020)

Effect of Base Sequence on G-Wire Formation in Solution
por: Spindler, Lea, et al.
Publicado: (2010)

Magnetically Tunable Liquid Crystal-Based Optical Diffraction Gratings
por: Bošnjaković, Dejan, et al.
Publicado: (2020)

Examining the language and behavioural profile in FTD and ALS-FTD
por: Saxon, Jennifer A, et al.
Publicado: (2017)

Crystal structure of parallel G-quadruplex formed by the two-repeat ALS- and FTD-related GGGGCC sequence
por: Geng, Yanyan, et al.
Publicado: (2021)

Screening for novel hexanucleotide repeat expansions at ALS- and FTD-associated loci
por: He, Fang, et al.
Publicado: (2016)

Characterizations of distinct parallel and antiparallel G-quadruplexes formed by two-repeat ALS and FTD related GGGGCC sequence
por: Zhou, Bo, et al.
Publicado: (2018)

The Role of Dipeptide Repeats in C9ORF72-Related ALS-FTD
por: Freibaum, Brian D., et al.
Publicado: (2017)

Inflammation in ALS/FTD pathogenesis
por: McCauley, Madelyn E., et al.
Publicado: (2018)

Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD
por: Zhou, Bo, et al.
Publicado: (2015)

Reversible Photoisomerization in Thin Surface Films from Azo-Functionalized Guanosine Derivatives
por: Ličen, Matjaž, et al.
Publicado: (2021)

Electrically Tuneable Optical Diffraction Gratings Based on a Polymer Scaffold Filled with a Nematic Liquid Crystal
por: Bošnjaković, Dejan, et al.
Publicado: (2021)

Emerging Perspectives on Dipeptide Repeat Proteins in C9ORF72 ALS/FTD
por: Schmitz, Alexander, et al.
Publicado: (2021)

Genetic screening in sporadic ALS and FTD
por: Turner, Martin R, et al.
Publicado: (2017)

Motor Neuron Susceptibility in ALS/FTD
por: Ragagnin, Audrey M. G., et al.
Publicado: (2019)

Effect of Material Composition on Tunable Surface Roughness of Magnetoactive Elastomers
por: Glavan, Gašper, et al.
Publicado: (2019)

Phenylalanine-tRNA aminoacylation is compromised by ALS/FTD-associated C9orf72 C4G2 repeat RNA
por: Malnar Črnigoj, Mirjana, et al.
Publicado: (2023)

The era of cryptic exons: implications for ALS-FTD
por: Mehta, Puja R., et al.
Publicado: (2023)

The carboxyl termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD
por: He, Fang, et al.
Publicado: (2020)

Guanosine Quadruplexes in Solution: A Small-Angle X-Ray Scattering Analysis of Temperature Effects on Self-Assembling of Deoxyguanosine Monophosphate
por: Mariani, P., et al.
Publicado: (2010)

Conformational dynamics of RNA G(4)C(2) and G(2)C(4) repeat expansions causing ALS/FTD using NMR and molecular dynamics studies
por: Taghavi, Amirhossein, et al.
Publicado: (2023)

Photoisomerizable Guanosine Derivative as a Probe for DNA Base-Pairing in Langmuir Monolayers
por: Ličen, M., et al.
Publicado: (2019)

Polarization patterning in ferroelectric nematic liquids via flexoelectric coupling
por: Sebastián, Nerea, et al.
Publicado: (2023)

FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD
por: Fujino, Yuzo, et al.
Publicado: (2023)

Oligonucleotide-Based Therapy for FTD/ALS Caused by the C9orf72 Repeat Expansion: A Perspective
por: Fernandes, Stephanie A., et al.
Publicado: (2013)

Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic
por: Lee, Youn-Bok, et al.
Publicado: (2013)

Unraveling the Role of RNA Mediated Toxicity of C9orf72 Repeats in C9-FTD/ALS
por: Kumar, Vijay, et al.
Publicado: (2017)

Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD
por: Wang, Shaopeng, et al.
Publicado: (2021)

Kinetics of Holographic Recording and Spontaneous Erasure Processes in Light-Sensitive Liquid Crystal Elastomers
por: Gregorc, Marko, et al.
Publicado: (2012)

Cognitive and behavioral features of c9FTD/ALS
por: Boeve, Bradley F, et al.
Publicado: (2012)

Linking hnRNP Function to ALS and FTD Pathology
por: Purice, Maria D., et al.
Publicado: (2018)

Lipid Metabolic Alterations in the ALS–FTD Spectrum of Disorders
por: Godoy-Corchuelo, Juan Miguel, et al.
Publicado: (2022)

ALS/FTD: Evolution, Aging, and Cellular Metabolic Exhaustion
por: Henderson, Robert David, et al.
Publicado: (2022)

Neural circuit and synaptic dysfunctions in ALS-FTD pathology
por: Mora, Santiago, et al.
Publicado: (2023)

Emerging Trends in the Field of Inflammation and Proteinopathy in ALS/FTD Spectrum Disorder
por: De Marchi, Fabiola, et al.
Publicado: (2023)

Retention of hexanucleotide repeat-containing intron in C9orf72 mRNA: implications for the pathogenesis of ALS/FTD
por: Niblock, Michael, et al.
Publicado: (2016)

Solution structure of a DNA quadruplex containing ALS and FTD related GGGGCC repeat stabilized by 8-bromodeoxyguanosine substitution
por: Brčić, Jasna, et al.
Publicado: (2015)

Repeat‐associated non‐AUG translation in C9orf72‐ALS/FTD is driven by neuronal excitation and stress
por: Westergard, Thomas, et al.
Publicado: (2019)

Targeting RNA G‐quadruplexes as new treatment strategy for C9orf72 ALS/FTD
por: Schludi, Martin H, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_6tmkhsnm63e1dokdfcn7mkok6t