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Advances in the Development Ubiquitin-Specific Peptidase (USP) Inhibitors

Ubiquitylation and deubiquitylation are reversible protein post-translational modification (PTM) processes involving the regulation of protein degradation under physiological conditions. Loss of balance in this regulatory system can lead to a wide range of diseases, such as cancer and inflammation....

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Detalles Bibliográficos
Autores principales: Chen, Shiyao, Liu, Yunqi, Zhou, Huchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123678/
https://www.ncbi.nlm.nih.gov/pubmed/33925279
http://dx.doi.org/10.3390/ijms22094546