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Functions of Thrombospondin-1 in the Tumor Microenvironment

The identification of thrombospondin-1 as an angiogenesis inhibitor in 1990 prompted interest in its role in cancer biology and potential as a therapeutic target. Decreased thrombospondin-1 mRNA and protein expression are associated with progression in several cancers, while expression by nonmaligna...

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Detalles Bibliográficos
Autores principales: Kaur, Sukhbir, Bronson, Steven M., Pal-Nath, Dipasmita, Miller, Thomas W., Soto-Pantoja, David R., Roberts, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123789/
https://www.ncbi.nlm.nih.gov/pubmed/33925464
http://dx.doi.org/10.3390/ijms22094570