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The Anti-Cancer Effects of a Zotarolimus and 5-Fluorouracil Combination Treatment on A549 Cell-Derived Tumors in BALB/c Nude Mice

Zotarolimus is a semi-synthetic derivative of rapamycin and a novel immunosuppressive agent used to prevent graft rejection. The pharmacological pathway of zotarolimus restricts the kinase activity of the mammalian target of rapamycin (mTOR), which potentially leads to reductions in cell division, c...

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Detalles Bibliográficos
Autores principales: Wu, Ching-Feng, Wu, Ching-Yang, Chiou, Robin Y.-Y., Yang, Wei-Cheng, Lin, Chuen-Fu, Wang, Chao-Min, Hou, Po-Hsun, Lin, Tzu-Chun, Kuo, Chan-Yen, Chang, Geng-Ruei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123799/
https://www.ncbi.nlm.nih.gov/pubmed/33925400
http://dx.doi.org/10.3390/ijms22094562