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Orexin A Enhances Pro-Opiomelanocortin Transcription Regulated by BMP-4 in Mouse Corticotrope AtT20 Cells

Orexin is expressed mainly in the hypothalamus and is known to activate the hypothalamic–pituitary–adrenal (HPA) axis that is involved in various stress responses and its resilience. However, the effects of orexin on the endocrine function of pituitary corticotrope cells remain unclear. In this stud...

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Detalles Bibliográficos
Autores principales: Fujisawa, Satoshi, Komatsubara, Motoshi, Tsukamoto-Yamauchi, Naoko, Iwata, Nahoko, Nada, Takahiro, Wada, Jun, Otsuka, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123825/
https://www.ncbi.nlm.nih.gov/pubmed/33925368
http://dx.doi.org/10.3390/ijms22094553