Development and Validation of a Sensitive, Specific and Reproducible UPLC-MS/MS Method for the Quantification of OJT007, A Novel Anti-Leishmanial Agent: Application to a Pharmacokinetic Study

OJT007 is a methionine aminopeptidase 1 (MetAP1) inhibitor with potent anti-proliferative effects against Leishmania Major. In order to study its pharmacokinetics as a part of the drug development process, a sensitive, specific, and reproducible ultra-high performance liquid chromatography-tandem ma...

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Detalles Bibliográficos
Autores principales: Rincon Nigro, Maria, Ma, Jing, Awosemo, Ololade Tosin, Xie, Huan, Olaleye, Omonike Arike, Liang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123827/
https://www.ncbi.nlm.nih.gov/pubmed/33925369
http://dx.doi.org/10.3390/ijerph18094624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123827/
https://www.ncbi.nlm.nih.gov/pubmed/33925369
http://dx.doi.org/10.3390/ijerph18094624

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