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Increased Extracellular Adenosine in Radiotherapy-Resistant Breast Cancer Cells Enhances Tumor Progression through A2AR-Akt-β-Catenin Signaling

SIMPLE SUMMARY: In our previous study, purinergic P2Y(2) receptor (P2Y(2)R) activation by ATP was found to play an important role in tumor progression and metastasis by regulating various responses in cancer cells and modulating crosstalk between cancer cells and endothelial cells (ECs). Therefore,...

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Detalles Bibliográficos
Autores principales: Jin, Hana, Lee, Jong-Sil, Kim, Dong-Chul, Ko, Young-Shin, Lee, Gyeong-Won, Kim, Hye-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123845/
https://www.ncbi.nlm.nih.gov/pubmed/33925516
http://dx.doi.org/10.3390/cancers13092105