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High-Fat Diet Aggravates Cerebral Infarct, Hemorrhagic Transformation and Neuroinflammation in a Mouse Stroke Model

Background: Stroke in context of type 2 diabetes (T2D) is associated with a poorer outcome than in non-diabetic conditions. We aimed at creating a new reproducible mouse model of stroke in impaired glucose tolerance conditions induced by high-fat diet. Methods: Adult C57BL6 mice were fed for 2 month...

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Detalles Bibliográficos
Autores principales: Grisotto, Coline, Taïlé, Janice, Planesse, Cynthia, Diotel, Nicolas, Gonthier, Marie-Paule, Meilhac, Olivier, Couret, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123851/
https://www.ncbi.nlm.nih.gov/pubmed/33925459
http://dx.doi.org/10.3390/ijms22094571