Combined Luteolin and Indole-3-Carbinol Synergistically Constrains ERα-Positive Breast Cancer by Dual Inhibiting Estrogen Receptor Alpha and Cyclin-Dependent Kinase 4/6 Pathway in Cultured Cells and Xenograft Mice

SIMPLE SUMMARY: Anti-cancer effects of bioactive compounds have been extensively investigated; however, the effective dosages of the bioactive compounds are too high to be obtained by oral intake. Our study aimed to assess if combined two bioactive compounds, luteolin (LUT) and indole-3-carbinol (I3...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyong, Zhang, Lijuan, Dai, Qi, Si, Hongzong, Zhang, Longyun, Eltom, Sakina E., Si, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123907/
https://www.ncbi.nlm.nih.gov/pubmed/33925607
http://dx.doi.org/10.3390/cancers13092116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123907/
https://www.ncbi.nlm.nih.gov/pubmed/33925607
http://dx.doi.org/10.3390/cancers13092116

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