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Combined Luteolin and Indole-3-Carbinol Synergistically Constrains ERα-Positive Breast Cancer by Dual Inhibiting Estrogen Receptor Alpha and Cyclin-Dependent Kinase 4/6 Pathway in Cultured Cells and Xenograft Mice
SIMPLE SUMMARY: Anti-cancer effects of bioactive compounds have been extensively investigated; however, the effective dosages of the bioactive compounds are too high to be obtained by oral intake. Our study aimed to assess if combined two bioactive compounds, luteolin (LUT) and indole-3-carbinol (I3...
Autores principales: | Wang, Xiaoyong, Zhang, Lijuan, Dai, Qi, Si, Hongzong, Zhang, Longyun, Eltom, Sakina E., Si, Hongwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123907/ https://www.ncbi.nlm.nih.gov/pubmed/33925607 http://dx.doi.org/10.3390/cancers13092116 |
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