Chromatin-Directed Proteomics Identifies ZNF84 as a p53-Independent Regulator of p21 in Genotoxic Stress Response

SIMPLE SUMMARY: Chemotherapy is a commonly applied anticancer treatment, however therapy-induced senescent growth arrest has been associated with aggressive disease recurrence. The p21 protein, encoded by CDKN1A, plays a vital role in the induction of senescence. Its transcriptional control by p53 i...

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Detalles Bibliográficos
Autores principales: Strzeszewska-Potyrała, Anna, Staniak, Karolina, Czarnecka-Herok, Joanna, Rafiee, Mahmoud-Reza, Herok, Marcin, Mosieniak, Grażyna, Krijgsveld, Jeroen, Sikora, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123910/
https://www.ncbi.nlm.nih.gov/pubmed/33925586
http://dx.doi.org/10.3390/cancers13092115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123910/
https://www.ncbi.nlm.nih.gov/pubmed/33925586
http://dx.doi.org/10.3390/cancers13092115

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