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α7 Nicotinic Acetylcholine Receptor Agonist PNU-282987 Ameliorates Cognitive Impairment Induced by Chronic Intermittent Hypoxia

PURPOSE: Cognitive impairment is an important complication of obstructive sleep apnea (OSA). Chronic intermittent hypoxia (CIH), the main pathophysiological characteristics of OSA, is closely related to cognitive dysfunction and may be mediated by alpha-7 nicotinic acetylcholine receptors (α7nAChR)....

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Detalles Bibliográficos
Autores principales: Shen, Hui, Meng, Yanling, Liu, Dan, Qin, Zheng, Huang, Hong, Pan, Lei, Wang, Wei, Kang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123952/
https://www.ncbi.nlm.nih.gov/pubmed/34007230
http://dx.doi.org/10.2147/NSS.S296701