microRNA-223 Deficiency Exacerbates Acute Inflammatory Response to Monosodium Urate Crystals by Targeting NLRP3

OBJECTIVE: MicroRNAs were identified as master-switch molecules limiting acute inflammatory response. This study investigated the potential role of microRNA (miR)-223 in the mechanism of gout. METHODS: Wild-type (WT) and miR-223 knock-out (KO) mice were used to evaluate the phenotypes of gout models...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Qi-Bin, Li, Ling-Qin, Zhang, Quan-Bo, He, Yong-Long, Mi, Qing-Sheng, Zhou, Jing-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123978/
https://www.ncbi.nlm.nih.gov/pubmed/34007200
http://dx.doi.org/10.2147/JIR.S307796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123978/
https://www.ncbi.nlm.nih.gov/pubmed/34007200
http://dx.doi.org/10.2147/JIR.S307796

Ejemplares similares