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microRNA-223 Deficiency Exacerbates Acute Inflammatory Response to Monosodium Urate Crystals by Targeting NLRP3

OBJECTIVE: MicroRNAs were identified as master-switch molecules limiting acute inflammatory response. This study investigated the potential role of microRNA (miR)-223 in the mechanism of gout. METHODS: Wild-type (WT) and miR-223 knock-out (KO) mice were used to evaluate the phenotypes of gout models...

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Detalles Bibliográficos
Autores principales:	Yang, Qi-Bin, Li, Ling-Qin, Zhang, Quan-Bo, He, Yong-Long, Mi, Qing-Sheng, Zhou, Jing-Guo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123978/ https://www.ncbi.nlm.nih.gov/pubmed/34007200 http://dx.doi.org/10.2147/JIR.S307796

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